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Borderline Personality Disorder across the Lifespan


On This Page:

Research on the Childhood Sexual Abuse/Borderline Connection and Memory Issues

Continuities of Diagnoses in Children/Adults?

Older Borderlines

Long-Term Outcome Studies


Still want more? Search dozens of professional psychiatric journal archives for specific topics: PubMed and BMJ


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Continuities of Diagnosis in Children/Adults?

Personality Disorders in Children and Adolescents
Book by Karen K. Bardenstein, Paulina F. Kernberg, Alan S. Weiner, 2000

Borderline Personality Disorder & Pediatrics
Excellent informative overview by Elizabeth A Finley-Belgrad, MD, eMedicine Journal, July 3, 2001

Multiple complex developmental disorder: the "multiple and complex" evolution of the "childhood borderline syndrome" construct
Abstract of a survey by Ad-Dab'bagh Y, Greenfield B., 2001

Dramatic-erratic personality disorder symptoms: I. Continuity from early adolescence into adulthood
Abstract of a longitudinal study by Crawford TN, Cohen P, Brook JS. 2001

Obect Relations and Referential Activity in Physically Abused Adolescents
Full-text write-up of a study by Lisa Jepson, Winter 1999
"[...] abused adolescents tended to have higher levels of two elements of referential activity (concreteness, imagery), indicating increased verbal ability to express emotional experience. While predicted correlations were found between object relations and referential activity for the nonabused group, the abused group showed higher symbolizing and verbalizing capacity, associated with more malevolent representations of relationships." The findings do not support the view that physically abused adolescents experience developmental lags, instead suggesting that they organize and use emotional and symbolizing processes differently from nonabused adolescents."

Diatheses and Stressors in Borderline Pathology of Childhood: The Role of Neuropsychological Risk and Trauma
Abstract of a study by PHYLLIS ZELKOWITZ, ED.D.; JOEL PARIS, M.D.; JASWANT GUZDER, M.D.; RONALD FELDMAN, M.D., 2001
"Both deficits in executive function and psychological trauma made significant and independent contributions to the variance in borderline pathology. Inclusion of both sets of risk factors produced a model that explained 48% of the variance in borderline diagnosis."

Identity disturbance in borderline personality disorder: an empirical investigation
Abstract of an article by Wilkinson-Ryan T, Westen D., 2000

Influence of child and adolescent psychiatric disorders on young adult personality disorder
Abstract of a study by Kasen S, Cohen P, Skodol AE, Johnson JG, Brook JS. 1999
Suggests that
"Childhood or adolescent axis I disorders may set in motion a chain of maladaptive behaviors and environmental responses that foster more persistent psychopathology over time."

recommended linkNeuropsychological factors associated with borderline pathology in children
by Joel Paris, June 1999
Full text article.
From the article:
"Borderline pathology in children is a syndrome characterized by a combination of externalizing and internalizing symptoms, accompanied by cognitive deficits (Bemporad et al., 1987; Kernberg, 1997). Although these symptoms resemble adult borderline personality, it is not clear whether they represent a unique disorder or a heterogeneous group better described by other diagnoses (Petri and Vela, 1990). However, a long-term follow-up study (Lofgren et al., 1991) has shown that borderline pathology in children is a precursor of adult personality disorders."

Applicability of personality disorder criteria to hospitalized adolescents: evaluation of internal consistency and criterion overlap
Full-text article by Daniel F. Becker, 1999
"Personality disorders are prevalent in adolescents and [...]they have concurrent validity (i.e., they are valid indicators of distress and dysfunction) but that they are relatively unstable over time."

recommended linkAntecedents of Personality Disorders in Young Adults
by Joseph M. Rey, M.D., 1999

Practice Parameters for the Assessment and Treatment of Children and Adolescents With Bipolar Disorder
Excellent, very informative full-text article by Jon McClellan. M.D., and John Werry, M.D.

recommended linkPosttraumatic Stress Disorder in Children
by Roy Lubit, MD, PhD, October 2001
Provides an excellent overview, as well as a detailed summary of the medications used in treating PTSD in children. Article may require registration (it's free) to read.

Sexual Obsessions in Obsessive-Compulsive Disorder
Jennifer B. Freeman,Ph.D.; Leonard, Henrietta L. M.D., 2000
This study examines the:
"[...] risk factors for the development of OCD and PTSD. Premorbid anxiety disorders may place children at higher risk for developing PTSD-type reactions after traumatic events as described by Asarnow and colleagues (1999). In some cases, exposure to trauma, depending on severity, may play a role in the development of some cases of OCD. One might speculate that this may be particularly relevant in those patients who are "at risk" to develop OCD."

Ten-Year Follow-up of Adolescent-Onset Anorexia Nervosa: Personality Disorders
by Elisabet Wentz Nilsson, 1999
"Personality disorder (PD) in clinical AN samples has been estimated to occur in 23% through 80% [...] Borderline PD (cluster B) is the PD most frequently associated with eating disorders."

A 6 year follow-up of childhood enuresis [bedwetting]: prevalence in adolescence and consequences for mental health
by Feehan M, McGee R, Stanton W, Silva PA., 1990
"Recent studies have shown an association between enuresis [bedwetting] and behavioural or emotional problems. The direction or causality of the association and its duration, however, remain unclear. This study followed a large group of children from ages 11 to 15 years and reported the prevalence of enuresis to age 13 years. The enuretic status of the sample at age 11 years was established relative to the history of enuresis at age 9 years. At age 11 years a significant association was found between enuresis and measures of psychopathology."

Association between behaviour at age 3 years and adult criminality
Abstract of British research by Stevenson J, Goodman R., 2001
(Interesting results, but bear in mind that this information is regressively extrapolated from already-convicted patients.)
"The risk of having any adult conviction was related to soiling, daytime enuresis, activity level and management difficulties, and that of having an adult violent offence to recent-onset daytime enuresis, management difficulties and temper tantrums. The only other predictors of later convictions were the child's gender and social competence at age 3 years."

History of childhood attention deficit/hyperactivity disorder symptoms and borderline personality disorder: A controlled study
Abstract of Italian research by Fossati A, Novella L, Donati D, Donini M, Maffei C., 2002

recommended linkPsychophysiological Responses in ADHD Boys With and Without Conduct Disorder: Implications for Adult Antisocial Behavior
by Sabine C. Herpertz in Psychiatric Times February 1996
"These findings give further support for a high persistence of antisocial behavior from childhood to adulthood, while no evidence was found that ADHD itself is associated with a predisposition to antisocial behavior."

Continuities between psychiatric disorders in adolescents and personality disorders in young adults
Abstract of a study by JM Rey, A Morris-Yates, M Singh, G Andrews and GW Stewart 1995

Continuity and discontinuity of psychopathology: a study of patients examined as children and as adults: The infancy of "adult personality disorders"
Abstract of a study by Manzano, et al, 1994

Development of personality disorders in children and adolescents with obsessive-compulsive disorder. A 6- to 22-year follow-up study.
Abstract of a study by Thomsen PH, Mikkelsen HU. 1993

Comorbidity of attention deficit hyperactivity disorder with conduct, depressive, anxiety, and other disorders
Abstract of a study by J Biederman, J Newcorn and S Sprich, 1991

A prospective follow-up study of so-called borderline children
Abstract of a study by DP Lofgren, J Bemporad, J King, K Lindem and G O'Driscoll, 1991

Comorbidity of conduct disorder and personality disorders in an incarcerated juvenile population
Abstract of a study by TD Eppright, JH Kashani, BD Robison and JC Reid, 1993

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Older Borderlines

Long-term Outcome in Personality Disorders
Abstract of 1993 study results by Michael H Stone, Columbia College of Physicians and Surgeons
recommended linkThis is the landmark study so often referred to when folks talk about BPs spontaneously "cooling off" with age. (The results of Stone's study are not proven anecdotally by the community of online nonBorderline spouses and loved ones, but this is probably a matter of statistics and self-selection.)
Stone published his results in the book: The Fate of Borderline Patients

Diminished Impulsivity in Older Patients With Borderline Personality Disorder
Abstract of a research study by Stevenson, Meares, and Comerford, Jan 2003
OBJECTIVE: The aim of this study was to test, in terms of impulsivity, the hypothesis that borderline personality disorder "burns out" with age. METHOD: Linear regression analyses, with age as a predictor variable, were conducted on subsection scores of the Revised Diagnostic Interview for Borderlines (DIB-R) for 123 individuals with a diagnosis of borderline personality disorder who were accepted into an outpatient-based psychotherapy program. The subsection scores of the DIB-R allow quantification of the core features of the disorder: affective disturbance, relationship disturbance, cognitive disturbance, and impulsive behavior. RESULTS: Older patients with borderline personality disorder showed less impulsivity than younger patients, but there was no difference in terms of affect disturbance, identity disturbance, and interpersonal problems. CONCLUSIONS: The view that borderline personality disorder burns out with age is supported in terms of impulsivity."

Personality Disorders in Late Life
Jennifer Q Morse MA and Thomas R Lynch PhD, 2000

Personality Disorders in Older Adults: Emerging Issues in Diagnosis and Treatment
Volume of studies edited by Robert C. Abrams and Richard A. Zweig, 1991
Includes:
1. Conceptual Overview of Personality Disorders in the Elderly John F. Clarkin, Lisa A. Spielman, and Ellen Klausner
2. Personality and Aging: A Psychotherapist Reflects Late in His Own Life Leston Havens
3. Personality Disorders in Adults: A Review Richard A. Zweig and Jennifer Hillman
4. Personality Disorders After Age 50: A Meta-Analytic Review of the Literature Robert C. Abrams and Sandra V. Horowitz
5. Personality Disorders and Treatment Outcome Theodore J. Gradman, Larry W. Thompson, and Dolores Gallagher-Thompson
recommended link[you can also purchase access to an online version of this and many other works on BPD at questia.com].

Personality Disorder Symptoms Predict Declines in Global Functioning and Quality of Life in Elderly Depressed Patients
Abstract of a research study by Robert Abrams et al, 2000

Pharmacological and psychotherapeutic treatment of personality disorders in the elderly
Abstract of research by De Leo D, Scocco P, Meneghel G.

Prospective follow-up study of borderline personality disorder: prognosis, prediction of outcome, and Axis II comorbidity
Full-text study, 1998.
"This prospective follow-up study found that almost 50% of former inpatients with BPD continue to test positive for BPD at 7 years follow-up, and these persistent BPD patients also had significantly more comorbid personality psychopathology. Borderline psychopathology at follow-up was primarily predicted by the level of borderline psychopathology recorded at the initial assessment."

A 27-year follow-up of patients with borderline personality disorder
Abstract of a report by Paris J. and Zweig, Frank H., Nov/Dec 2001
"Sixty-four patients with borderline personality disorder (BPD) were followed up for a mean of 27 years. [...] Most patients showed significant improvement as compared to a previous 15-year follow-up, with only five currently meeting criteria for BPD. [...] Fourteen subjects met SCID criteria for dysthymia, and this subgroup had a significantly poorer outcome on all measures. The total percentage of suicides from the original cohort has reached 10.3%, with 18.2% of all patients now deceased."

Self-harm behaviors across the life cycle: a pilot study of inpatients with borderline personality disorder
Abstract of a study by Sansone RA, Gaither GA, Songer DA., May/June 2002
"The purpose of this study was to explore, throughout the life cycle, the prevalence of self-harm behaviors among psychiatric inpatients with and without borderline personality disorder (BPD). Psychiatric inpatients with BPD (n = 43) were compared to those without BPD (n = 40) with regard to self-reported self-harm behaviors during their lifetime. The mean number of self-harm behaviors, including high-lethal behaviors (i.e., suicide attempts, cutting oneself, overdosing), among those with BPD dramatically increased between the ages of 18 and 24 years and was sustained through ages 50 to 59 years. Non-BPD patients showed a similar pattern, but the means were notably less. These data suggest that the behavioral "burn out" theory of personality disorders does not necessarily occur among inpatients with BPD."

Borderline Personality Disorder In The Elderly
Abstract of a study by Hill, E.L., Hersen, M., Van Hasselt, V., Journal of Clinical Geropsychology, Oct 1998
"Few studies have investigated borderline personality disorder (bpd) among the elderly. This paper suggests that bpd persists into older adulthood."

recommended linkClinical Characteristics of Older Psychiatric Inpatients with Borderline Personality Disorder
by Brian Trappler and Jill Backfield, Spring 2001
Unfortunately this is only an abstract (full-text article requires subscription) but it's still quite interesting information:
"Rather than suggesting a diminution of psychopathology as BPD patients age, the results of this investigation indicate that their persistent difficulties may only be altering in content and in pathological adaptation to changing needs."

Personality Disorders in Elderly Patients With Dysthymic Disorder
Abstract of an article by D.P. Devanand, M.D., et al, Aug 2000

Borderline personality disorder in the elderly: a case study
by Siegel DJ, Small GW, 1986

Previous psychiatric history as a risk factor for late-life dementia: a population-based case-control study
by Brian Cooper, 1998

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Long-Term Outcome Studies

recommended linkLong-term Outcome in Personality Disorders
Abstract of 1993 study results by Michael H Stone, Columbia College of Physicians and Surgeons
This is the landmark study so often referred to when folks talk about BPs spontaneously "cooling off" with age; remains to be proven anecdotally by the community of online nonBorderline spouses and loved ones.
Stone published his results in the book: The Fate of Borderline Patients

Day treatment for personality disorders: a review of research findings.
Abstract of a study by Ogrodniczuk JS, Piper WE. 2001
Full-text article may be purchased for a fee

The 'therapeutic community'; outcome evaluation
by Kingsley Norton and Fiona Warren
"It is now evident that people with personality disorder can sometimes be helped to change. The notion that personality disorder is immutable is outmoded and unacceptable."
Excellent, detailed article discussing the problems with 'treatment outcome' studies and personality disorders.

Outcome in borderline disorders. A literature review
Abstract of a study by Rothenhausler HB, Kapfhammer HP., 1999
Full-text article may be purchased for a fee

Prospective follow-up study of borderline personality disorder: prognosis, prediction of outcome, and Axis II comorbidity
Full-text study, 1998. "This prospective follow-up study found that almost 50% of former inpatients with BPD continue to test positive for BPD at 7 years follow-up, and these persistent BPD patients also had significantly more comorbid personality psychopathology. Borderline psychopathology at follow-up was primarily predicted by the level of borderline psychopathology recorded at the initial assessment."

A 27-year follow-up of patients with borderline personality disorder
Abstract of a report by Paris J. and Zweig, Frank H., Nov/Dec 2001
"Sixty-four patients with borderline personality disorder (BPD) were followed up for a mean of 27 years. [...] Most patients showed significant improvement as compared to a previous 15-year follow-up, with only five currently meeting criteria for BPD. [...] Fourteen subjects met SCID criteria for dysthymia, and this subgroup had a significantly poorer outcome on all measures. The total percentage of suicides from the original cohort has reached 10.3%, with 18.2% of all patients now deceased."

Effects of Client-Centered Psychotherapy for Personality Disorders Alone and in Combination with Psychopharmacological Treatment. an empirical follow-up study
British study by Teusch L; Bohme H; Finke J; Gastpar M., 2001
"There is an increasing interest concerning the treatment of patients with personality disorders (PD) in data on the efficacy of psychotherapeutic strategies especially when combined with medication. Methods: The efficacy of an inpatient client-centered treatment program (CCT) was studied prospectively in 142 patients with PD and additional depressive, anxiety or eating disorders (ICD-10). Results: Significant improvements in depression, self-esteem and social adjustment were achieved up to discharge, which remained stable at the 1-year follow-up. The efficacy with regard to individual variables or the total result could not be further enhanced by a combination with psychopharmacological treatment (CCT + MED), consisting mainly of antidepressants. Within the subgroups of patients with socially deviant (F60.0-2), emotionally unstable/borderline (F60.3) and histrionic/narcissistic PD (F60.4, F60.8), CCT was significantly superior to CCT + MED in the reduction of depression (Bech-Rafaelsen Melancholia Scale ratings), whereas the response was enhanced by medication in the subgroup of patients with socially dependent 'cluster C' PD (F60.5-7). Conclusions: The results are discussed with regard to client-centered therapeutic concepts and to the further development of differential combination strategies."

Treatment of Personality Disorders in an Era of Limited Resources
by Eric Plakun, M.D.

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This Page Last Updated: May 26, 2003

Helen's World of BPD Resources

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